Publicación: Las plantas como fuente de compuestos fotoprotectores frente al daño en el ADN producido por la radiación ultravioleta
dc.contributor.author | Fuentes Lorenzo, Jorge L. | |
dc.contributor.corporatename | Academia Colombiana de Ciencias Exactas, Físicas y Naturales | spa |
dc.date.accessioned | 2021-12-09T23:26:51Z | |
dc.date.available | 2021-12-09T23:26:51Z | |
dc.date.issued | 2019-09-25 | |
dc.description.abstract | La fotoprotección es una estrategia preventiva y terapéutica frente al cáncer y el envejecimiento de la piel. En el presente trabajo se revisan los efectos biológicos adversos de la radiación ultravioleta, los conceptos básicos relevantes de la fotoprotección y los métodos para llevar a cabo su medición. Asimismo, se resumen los resultados obtenidos de la caracterización radiobiológica y genética del modelo experimental (SOS Chromotest) usado para la bioprospección de extractos y moléculas de origen vegetal con potencial en fotoprotección. Además, se presentan datos sobre la eficacia fotoprotectora y las estimaciones del efecto antigenotóxico de aceites esenciales y extractos obtenidos de especies de plantas, así como de los compuestos mayoritarios de los aceites y extractos promisorios analizados en este estudio. Por último, se postulan posibles mecanismos de acción de algunas moléculas relevantes. Los resultados se presentan y discuten destacando su potencial uso para el desarrollo de bloqueadores solares multifuncionales. | spa |
dc.description.abstract | Photoprotection is a preventive and therapeutic strategy against skin cancer and photoaging. In the present work, we review the adverse biological effects of the ultraviolet radiation, the basic concepts with relevance in photoprotection, and the methods to carry out its measurement. Likewise, we summarized the main results obtained from the radiobiological and genetic characterization of the SOS Chromotest model, which we used for bioprospecting photoprotective activity of plant extracts and molecules. Besides, we showed photoprotective efficacy and/or antigenotoxicity estimates of plant essential oils and extracts, as well as of the major compounds of promissory oils and extracts analyzed in our study. Finally, action mechanisms of the relevant molecules are postulated. These results are presented and discussed considering their potential use to formulate multifunctional sunscreen. | eng |
dc.format.mimetype | application/pdf | spa |
dc.identifier.doi | https://doi.org/10.18257/raccefyn.841 | |
dc.identifier.uri | https://repositorio.accefyn.org.co/handle/001/1162 | |
dc.language.iso | spa | spa |
dc.publisher | Academia Colombiana de Ciencias Exactas, Físicas y Naturales | spa |
dc.publisher.place | Bogotá, Colombia | spa |
dc.relation.citationendpage | 562 | spa |
dc.relation.citationissue | 168 | spa |
dc.relation.citationstartpage | 550 | spa |
dc.relation.citationvolume | 43 | spa |
dc.relation.ispartofjournal | Revista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturales | spa |
dc.rights | Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International | spa |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.rights.coar | http://purl.org/coar/access_right/c_abf2 | spa |
dc.rights.license | Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) | spa |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | spa |
dc.source | Revista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturales | spa |
dc.subject.proposal | Radiación ultravioleta | spa |
dc.subject.proposal | Ultraviolet radiation | eng |
dc.subject.proposal | Fotoprotección | spa |
dc.subject.proposal | Photoprotection | eng |
dc.subject.proposal | Antigenotoxicidad | spa |
dc.subject.proposal | Antigenotoxicity | eng |
dc.subject.proposal | Metabolitos secundarios de plantas | spa |
dc.subject.proposal | Plant secondary metabolites | eng |
dc.title | Las plantas como fuente de compuestos fotoprotectores frente al daño en el ADN producido por la radiación ultravioleta | spa |
dc.type | Artículo de revista | spa |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | spa |
dc.type.coarversion | http://purl.org/coar/version/c_970fb48d4fbd8a85 | spa |
dc.type.content | DataPaper | spa |
dc.type.driver | info:eu-repo/semantics/article | spa |
dc.type.redcol | http://purl.org/redcol/resource_type/ART | spa |
dc.type.version | info:eu-repo/semantics/publishedVersion | spa |
dcterms.audience | Estudiantes, Profesores, Comunidad científica colombiana | spa |
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