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Suplemento Conexión de Biología y Química vía Síntesis Orgánica dirigida a la Diversidad molecular

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dc.contributor.authorKouznetsov, Vladimir V.
dc.contributor.corporatenameAcademia Colombiana de Ciencias Exactas, Físicas y Naturalesspa
dc.date.accessioned2021-10-15T17:11:39Z
dc.date.available2021-10-15T17:11:39Z
dc.date.issued2014-11-28
dc.description.abstractEl enorme progreso en el entendimiento de los sistemas biológicos y del funcionamiento de los fármacos dentro del cuerpo humano se debe a la unión de la química y la biología y a la aplicación inteligente de los principios y técnicas de la química orgánica. Ésta juega el papel de iniciador en el descubrimiento biológico impulsando el diseño y desarrollo de nuevos fármacos. Utilizando tácticas sintéticas modernas de la química orgánica, la síntesis dirigida a la diversidad permite preparar diversas moléculas (fármacos, agentes biológicos) que son valiosos modelos para el estudio de las complejas interacciones biológicas de los organismos vivos. Los resultados y logros del LQOBio se discuten en esta revisión prestando atención al desarrollo de algunos aspectos de la síntesis verde y la biología química que ha venido haciendo el LQOBio estos últimos años.spa
dc.description.abstractThe enormous progress in the understanding of biological systems and the functioning of the drugs within the human body is due to the union of chemistry and biology and the intelligent application of the principles and techniques of organic chemistry. This plays the role of initiator in biological discovery driving the design and development of new drugs. Using tactics of modern synthetic organic chemistry, diversity-directed synthesis allows preparation of various molecules (drugs, biological agents) that are valuable models for the study of complex biological interactions of living organisms. The results and achievements of the LQOBio are discussed in this review with attention to the development of some aspects of green synthesis and chemical biology that has been doing the LQOBio recent years.eng
dc.format.extent13 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.doihttps://doi.org/10.18257/raccefyn.159
dc.identifier.urihttps://repositorio.accefyn.org.co/handle/001/832
dc.language.isospaspa
dc.publisherAcademia Colombiana de Ciencias Exactas, Físicas y Naturalesspa
dc.publisher.placeBogotá, Colombiaspa
dc.relation.citationendpage141spa
dc.relation.citationissueSuplementospa
dc.relation.citationstartpage129spa
dc.relation.citationvolume38spa
dc.relation.ispartofjournalRevista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturalesspa
dc.rightsCreative Commons Attribution-NonCommercial-ShareAlike 4.0 Internationalspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa
dc.rights.licenseAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/spa
dc.subject.proposalSíntesis dirigida a la diversidadspa
dc.subject.proposalDiversity Oriented Synthesiseng
dc.subject.proposalMoléculas pequeñasspa
dc.subject.proposalSmall moleculeseng
dc.subject.proposalHeterociclosspa
dc.subject.proposalHeterocycleseng
dc.subject.proposalBioensayos in vitro e in vivospa
dc.subject.proposalIn vitro and in vivo bioassayseng
dc.titleSuplemento Conexión de Biología y Química vía Síntesis Orgánica dirigida a la Diversidad molecularspa
dc.typeArtículo de revistaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.coarversionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.type.contentDataPaperspa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.redcolhttp://purl.org/redcol/resource_type/ARTREFspa
dc.type.versioninfo:eu-repo/semantics/publishedVersionspa
dcterms.audienceEstudiantes, Profesores, Comunidad científicaspa
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