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dc.contributor.authorAbonia, Rodrigo-
dc.contributor.authorC. García, Andres-
dc.date.accessioned2022-11-03T23:37:55Z-
dc.date.available2022-11-03T23:37:55Z-
dc.date.issued2021-12-13-
dc.identifier.issn0370-3908spa
dc.identifier.urihttps://repositorio.accefyn.org.co/handle/001/2019-
dc.description.abstractLos productos de Knoevenagel diversamente sustituidos se sometieron a reducción con NaBH4 en una solución de MeOH/dioxano a 70 oC. En todos los casos se consiguió una reducción selectiva de su doble enlace C=C. Las condiciones de reducción toleraron una variedad de grupos funcionales, aunque los productos aldólicos simples o Claisen-Schmidt mostraron ser menos selectivos hacia la reducción C=C y, por el contrario, el enlace C=O se redujo en estas condiciones de reacción. Además, la selectividad de la reducción química mediada por NaBH4 se comparó con la hidrogenación catalítica mediada por Raney-Nickel clásica para encontrar similitudes y diferencias. Además, al tratar de explicar el proceso reductor selectivo mediado por NaBH4, se propuso una vía mecanicista plausible a este respecto.spa
dc.description.abstractDiversely substituted Knoevenagel products were subjected to reduction with NaBH4 in MeOH/pdioxane solution at 70 oC. Selectively reduction of their C=C double bond was achieved in all cases. Reduction conditions tolerated a variety of functional groups although simple aldolic or Claisen-Schmidt products showed to be less selective toward C=C reduction and on the contrary C=O bond was reduced under these reaction conditions. Additionally, selectivity of the NaBH4-mediated chemical reduction was compared with the classical Raney-Nickel-mediated catalytic hydrogenation in order to find similarities and differences. Moreover, trying to explain the selective NaBH4-mediated reductive process a plausible mechanistic pathway was proposed in this regard.eng
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherRevista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturalesspa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0/spa
dc.titleUso de una mezcla tibia de dioxano/MeOH/NaBH4 como medio conveniente para la reducción química selectiva del doble enlace C=C en sistemas α,β-insaturadosspa
dc.titleUsing a warm dioxane/MeOH/NaBH4 mixture as convenient medium for the selective chemical reduction of the C=C double bond in α,β-unsaturated systemseng
dc.typeArtículo de revistaspa
dcterms.audienceEstudiantes, Profesores, Comunidad científica.spa
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dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.versioninfo:eu-repo/semantics/updatedVersionspa
dc.rights.creativecommonsAtribución-NoComercial-CompartirIgual 4.0 Internacional (CC BY-NC-SA 4.0)spa
dc.identifier.doihttps://doi.org/10.18257/raccefyn.1465-
dc.subject.proposalChalconesspa
dc.subject.proposalChalconeseng
dc.subject.proposalKnoevenagel productosspa
dc.subject.proposalKnoevenagel productseng
dc.subject.proposalSistemas α,β-insaturadosspa
dc.subject.proposalα,β-Unsaturated systemseng
dc.subject.proposalReducciones selectivasspa
dc.subject.proposalSelective reductionseng
dc.subject.proposalReducciones mediadas por NaBH4spa
dc.subject.proposalNaBH4-mediate reductionseng
dc.subject.proposalHidrogenación catalíticaspa
dc.subject.proposalCatalytic hydrogenationeng
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa
dc.relation.ispartofjournalRevista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturalesspa
dc.relation.citationvolume45spa
dc.relation.citationstartpage1232spa
dc.relation.citationendpage1245spa
dc.contributor.corporatenameAcademia Colombiana de Ciencias Exactas, Físicas y Naturalesspa
dc.identifier.eissn2382-4980spa
dc.relation.citationissue177spa
dc.type.contentTextspa
dc.type.redcolhttp://purl.org/redcol/resource_type/ARTspa
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oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
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