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dc.contributor.author | Gómez Grosso, Luis A. | - |
dc.date.accessioned | 2021-10-15T14:35:20Z | - |
dc.date.available | 2021-10-15T14:35:20Z | - |
dc.date.issued | 2013-12-15 | - |
dc.identifier.uri | https://repositorio.accefyn.org.co/handle/001/783 | - |
dc.description.abstract | El objetivo de este estudio fue evaluar el preacondicionamiento isquémico, PCI, en cardiomiocitos ventriculares de cobayo adultos individuales y evaluar el perfil de expresión diferencial de microRNAs en estas células. Una supervisión de la morfología, de la actividad metabólica de las células cardíacas individuales aisladas en tiempo real, permite una evaluación de los cambios en la viabilidad de los cardiomiocitos y proporciona evidencia experimental de que el PCI tiene acción citoprotectora directa mediante la promoción de la supervivencia in vitro. La protección cardiaca por PCI asociada con la expresión diferencial de microRNAs específicos en cardiomicitos adultos aislados sugiere que algunos miRNAs están involucrados en lesión y cardioprotección. | spa |
dc.description.abstract | The aim of this study was to evaluate the ischemic preconditioning, PCI, in single quiescent adult guinea-pig ventricular myocytes and assess the differential expression of microRNAs in these cells. Monitoring of the morphology of the metabolic activity of individual cardiac cells isolated in real time, allows evaluation of changes in the viability of the cardiomyocytes and provides experimental evidence that PCI has direct cytoprotective action by promoting survival in vitro. PCI cardiac protection associated with the differential expression of specific microRNAs in isolated adult cardiomyocytes suggests that miRNAs are involved in some injury and cardioprotection. | eng |
dc.format.extent | 15 páginas | spa |
dc.format.mimetype | application/pdf | spa |
dc.language.iso | spa | spa |
dc.publisher | Academia Colombiana de Ciencias Exactas, Físicas y Naturales | spa |
dc.rights | Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International | spa |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | spa |
dc.title | Preacondicionamiento isquémico en cardiomiocitos ventriculares aislados. Identificación y expresión de algunos microRNAs asociados | spa |
dc.type | Artículo de revista | spa |
dcterms.audience | Estudiantes, Profesores, Comunidad científica | spa |
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dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.type.driver | info:eu-repo/semantics/article | spa |
dc.type.version | info:eu-repo/semantics/publishedVersion | spa |
dc.rights.creativecommons | Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) | spa |
dc.identifier.doi | https://doi.org/10.18257/raccefyn.26 | - |
dc.subject.proposal | Cardioprotección | spa |
dc.subject.proposal | Cardioprotection | eng |
dc.subject.proposal | Preacondicionamiento | spa |
dc.subject.proposal | Preconditioning | eng |
dc.subject.proposal | Ensayo de MTT | spa |
dc.subject.proposal | MTT assay | eng |
dc.subject.proposal | Tiempo real | spa |
dc.subject.proposal | Real time | eng |
dc.subject.proposal | Cardiomiocitos | spa |
dc.subject.proposal | Cardiomyocyte | eng |
dc.subject.proposal | Viabilidad | spa |
dc.subject.proposal | Viability | eng |
dc.subject.proposal | Isquemia | spa |
dc.subject.proposal | Injury | eng |
dc.subject.proposal | Dinitrofenol | spa |
dc.subject.proposal | Dinitrophenol | eng |
dc.subject.proposal | Adenosina | spa |
dc.subject.proposal | Adenosine | eng |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | spa |
dc.relation.ispartofjournal | Revista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturales | spa |
dc.relation.citationvolume | 37 | spa |
dc.relation.citationstartpage | 433 | spa |
dc.relation.citationendpage | 447 | spa |
dc.publisher.place | Bogotá, Colombia | spa |
dc.contributor.corporatename | Academia Colombiana de Ciencias Exactas, Físicas y Naturales | spa |
dc.relation.citationissue | 145 | spa |
dc.type.content | DataPaper | spa |
dc.type.redcol | http://purl.org/redcol/resource_type/ART | spa |
oaire.accessrights | http://purl.org/coar/access_right/c_abf2 | spa |
oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 | spa |
Appears in Collections: | BA. Revista de la Academia Colombiana de Ciencias Exactas Físicas y Naturales |
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1. Preacondicionamiento isquémico en cardiomiocitos.pdf | Ciencias Biomédicas | 562.82 kB | Adobe PDF | View/Open |
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