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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Franco, L. | spa |
| dc.contributor.author | Najvar, L. | spa |
| dc.contributor.author | Gómez, B. L. | spa |
| dc.contributor.author | Restrepo, S. | spa |
| dc.contributor.author | Graybill, J. R. | spa |
| dc.contributor.author | Restrepo Moreno, Ángela | spa |
| dc.date.accessioned | 2021-11-16T16:50:07Z | - |
| dc.date.available | 2021-11-16T16:50:07Z | - |
| dc.date.issued | 1998 | - |
| dc.identifier.issn | 00029637 | - |
| dc.identifier.uri | https://repositorio.accefyn.org.co/handle/001/1054 | - |
| dc.description.abstract | Se indujo fibrosis pulmonar tras la inoculación de conidios de Paracoccidioides brasiliensis por vía intranasal en ratones BALB / c. La fibrosis se asoció con la formación de granulomas, aumento de la hidroxiprolina pulmonar y aumentos sostenidos del factor de necrosis tumoral tisular alfa y del factor de crecimiento transformante beta. Este estudio sugiere un papel de estas citocinas en la generación de fibrosis pulmonar asociada con enfermedades infecciosas granulomatosas crónicas. | eng |
| dc.description.abstract | Pulmonary fibrosis was induced following inoculation of Paracoccidioides brasiliensis conidia intranasally in BALB/c mice. Fibrosis was associated with formation of granulomas, increase in lung hydroxyproline, and sustained increases in tissue tumor necrosis factor-alpha and transforming growth factor-beta. This study suggests a role for these cytokines in generation of pulmonary fibrosis associated with chronic granulomatous infectious diseases. | spa |
| dc.language | eng | - |
| dc.publisher | American Society of Tropical Medicine and Hygiene USA | - |
| dc.relation.uri | https://doi.org/10.4269/ajtmh.1998.58.424 | - |
| dc.title | Experimental pulmonary fibrosis induced by paracoccidioides brasiliensis conidia: measurement of local host responses | eng |
| dc.type | article | eng |
| dc.rights.accessrights | info:eu-repo/semantics/openAccess | eng |
| dc.subject.lemb | Fibrosis pulmonar | spa |
| dc.subject.lemb | Investigación aplicada | spa |
| dc.type.driver | info:eu-repo/semantics/article | eng |
| dc.type.local | Artículo | spa |
| dc.identifier.doi | 10.4269/ajtmh.1998.58.424 | - |
| dc.subject.keywords | Paracoccidioides brasiliensis | spa |
| dc.citation.journalTitle | The American Journal of Tropical Medicine and Hygiene | - |
| dc.relation.citationvolume | 58 | - |
| dc.rights.local | Acceso abierto | - |
| dc.citation.spage | 424 | - |
| dc.citation.epage | 430 | - |
| dc.contributor.director | journal@ajtmh.org | - |
| dc.relation.citationissue | 4 | - |
| dc.source.bibliographiccitation | Franco, L.; Najvar, L.; Gómez, B. L.; Restrepo, S.; Graybill, J. R. & Restrepo, A. (1998). Experimental pulmonary fibrosis induced by paracoccidioides brasiliensis conidia: measurement of local host responses. American Journal of Tropical Medicine and Hygiene, 58(4), 424-430 | - |
| Appears in Collections: | DHAE Paracoccidioidomicosis. Inmunología | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| experimental pulmonary.pdf | 7.59 MB | Adobe PDF |  View/Open |
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