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dc.contributor.authorFranco, L.spa
dc.contributor.authorNajvar, L.spa
dc.contributor.authorGómez, B. L.spa
dc.contributor.authorRestrepo, S.spa
dc.contributor.authorGraybill, J. R.spa
dc.contributor.authorRestrepo Moreno, Ángelaspa
dc.date.accessioned2021-11-16T16:50:07Z-
dc.date.available2021-11-16T16:50:07Z-
dc.date.issued1998-
dc.identifier.issn00029637-
dc.identifier.urihttps://repositorio.accefyn.org.co/handle/001/1054-
dc.description.abstractSe indujo fibrosis pulmonar tras la inoculación de conidios de Paracoccidioides brasiliensis por vía intranasal en ratones BALB / c. La fibrosis se asoció con la formación de granulomas, aumento de la hidroxiprolina pulmonar y aumentos sostenidos del factor de necrosis tumoral tisular alfa y del factor de crecimiento transformante beta. Este estudio sugiere un papel de estas citocinas en la generación de fibrosis pulmonar asociada con enfermedades infecciosas granulomatosas crónicas.eng
dc.description.abstractPulmonary fibrosis was induced following inoculation of Paracoccidioides brasiliensis conidia intranasally in BALB/c mice. Fibrosis was associated with formation of granulomas, increase in lung hydroxyproline, and sustained increases in tissue tumor necrosis factor-alpha and transforming growth factor-beta. This study suggests a role for these cytokines in generation of pulmonary fibrosis associated with chronic granulomatous infectious diseases.spa
dc.languageeng-
dc.publisherAmerican Society of Tropical Medicine and Hygiene USA-
dc.relation.urihttps://doi.org/10.4269/ajtmh.1998.58.424-
dc.titleExperimental pulmonary fibrosis induced by paracoccidioides brasiliensis conidia: measurement of local host responseseng
dc.typearticleeng
dc.rights.accessrightsinfo:eu-repo/semantics/openAccesseng
dc.subject.lembFibrosis pulmonarspa
dc.subject.lembInvestigación aplicadaspa
dc.type.driverinfo:eu-repo/semantics/articleeng
dc.type.localArtículospa
dc.identifier.doi10.4269/ajtmh.1998.58.424-
dc.subject.keywordsParacoccidioides brasiliensisspa
dc.citation.journalTitleThe American Journal of Tropical Medicine and Hygiene-
dc.relation.citationvolume58-
dc.rights.localAcceso abierto-
dc.citation.spage424-
dc.citation.epage430-
dc.contributor.directorjournal@ajtmh.org-
dc.relation.citationissue4-
dc.source.bibliographiccitationFranco, L.; Najvar, L.; Gómez, B. L.; Restrepo, S.; Graybill, J. R. & Restrepo, A. (1998). Experimental pulmonary fibrosis induced by paracoccidioides brasiliensis conidia: measurement of local host responses. American Journal of Tropical Medicine and Hygiene, 58(4), 424-430-
Appears in Collections:DHAE Paracoccidioidomicosis. Inmunología

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